We Offer.
Our Service
One-Stop Preclinical Drug
Development Solutions
We provide top-notch CRO services for drug development. With a team of experienced professionals and state-of-the-art technology, we have the capability to conduct a wide range of preclinical studies, including pharmacology, toxicology, formulation development, and bioanalytical services. Our services are customizable to meet the specific needs of each client, and our expertise in regulatory compliance ensures that all studies are conducted in accordance with the highest industry standards. With our commitment to quality, reliability, and timeliness, we strive to be a trusted partner in the drug development process for our clients.
Formulation Development and Optimization
- Difficulty to deliver drugs: poor solubility, permeability, selectivity.
- Small molecules, proteins, nucleic acids
- Liposomes, lipid nanoparticles (LNP), polymeric conjugates, polymeric micelles, emulsions, and self-emulsifying DDS
- Lyophilization
- Non-GLP scale up
Formulation Characterization
- DLS; TEM; cryo-EM
- Drug release kinetics in different medium
- Method development for quantifying payloads and excipients
- Preliminary storage stability test
Cell-based and In vitro assays
- Cytotoxicity and immunotoxicity
- Cellular uptake and intracellular trafficking (confocal microscopy)
- Cell transfection of nucleic acids
- Cell sorting (FACS)
- Immunostaining
- Human tissue substitutes (skin, nose, mouth)
- Endotoxin and sterility
Animal Studies
- Preliminary safety study (MTD; blood chemistry; serology; tissue histology; immunohistochemistry)
- Pharmacokinetic study
- Efficacy study (cancer; pain; depression; diabetes; liver diseases; inflammatory diseases)